Internacionalização

Internacionalização

O incentivo para a realização de intercâmbios internacionais tem sido um dos principais focos do Programa de Pós-graduação Interdisciplinar em Ciências da Saúde. O estabelecimento e a consolidação de parcerias com pesquisadores no exterior é de extrema importância para possibilitar o intercâmbio entre discentes e docentes. Desta forma, segue abaixo a descrição das principais parcerias e convênios realizados com pesquisadores e instituições de pesquisa no exterior desde a formação do programa.

Instituições Parceiras

Canadian Institutes of Health Research
Coorientação pela Profa. Dra. Ana Maria Forti Barela da aluna Andresa Rosane Marinho que está desenvolvendo a tese de doutorado intitulada “Aquatic-supported weight shifting as a preliminary locomotor trainning approach to enhance postural control after an incomplete spinal cord injury” no CANADIAN INSTITUTES OF HEALTH RESEARCH sob a orientação da Profa. Dra. Molly Verrier.

Curtin University of Technology/Austrália
Profa. Dra. Tania Cristina Pithon-Curi: professora visitante da CURTIN UNIVERSITY OF TECHNOLOGY/Austrália

Metabolic regulation of the immune system Laboratory
Prof. Dr. Philip Newsholme

Docentes com colaborações: Tania C. Pithon-Curi, Renata Gorjão, Sandro M. Hirabara e Elaine Hatanaka

Abaixo segue a lista dos artigos publicados, resultado da cooperação e intercâmbio há 13 anos entre os pesquisadores de nosso programa e o Prof. Dr. Philip Newsholme:

• HATANAKA, E.; DERMARGOS, A.; HIRATA, A. E. ; Vinolo MAR ; CARPINELLI, A. R. ; Newsholme P ; ARMELIN, H. A. ; Curi, Rui. Oleic, Linoleic and Linolenic Acids Increase ROS Production by Fibroblasts via NADPH Oxidase Activation. Plos One, p. 1, 2013.

• BORTOLON, JR; SILVA JUNIOR, AJA; MURATA, GM; NEWSHOLME, P; CURI, R; PITHON-CURI, TC ; HATANAKA, E. Persistence of Inflammatory Response to Intense Exercise in Diabetic Rats. Experimental Diabetes Research (Online), v. 2012, p. 1-8, 2012.

• TAKAHASHI HK, CAMBIAGHI TD, LUCHESSI AD, HIRABARA SM, VINOLO MA, NEWSHOLME P, CURI R. Activation of survival and apoptotic signaling pathways in lymphocytes exposed to palmitic acid. J Cell Physiol. v. 227, n.1, p.339-50, 2012.

• MAGDALON J, HATANAKA E, ROMANATTO T, RODRIGUES HG, KUWABARA WM, SCAIFE C, NEWSHOLME P,CURI R. A proteomic analysis of the functional effects of fatty acids in NIH 3T3 fibroblasts. Lipids Health Dis. v.10, p.218, 2011.

• NEWSHOLME P, ABDULKADER F, REBELATO E, ROMANATTO T, PINHEIRO CH, VITZEL KF, SILVA EP, BAZOTTE RB, PROCOPIO J, CURI R, GORJAO R, PITHON-CURI TC. Amino acids and diabetes: implications for endocrine, metabolic and immune function. Front Biosc, 16:315-39, 2011.

• VINOLO MA, HATANAKA E, LAMBERTUCCI RH, NEWSHOLME P, CURI R. Effects of short chain fatty acids on effector mechanisms of neutrophils.Cell Biochem Funct. Jan;27(1):48-55. doi: 10.1002/cbf.1533, 2009.

• NEWSHOLME P, HABER EP, HIRABARA SM, REBELATO EL, PROCOPIO J, MORGAN D, OLIVEIRA-EMILIO HC, CARPINELLI AR, CURI R. Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity. J Physiol. Aug 15;583(Pt 1):9-24. Epub 2007 Jun 21. Review, 2007.

• CURI R, NEWSHOLME P, PROCOPIO J, LAGRANHA C, GORJÃO R, PITHON-CURI TC. Glutamine, gene expression, and cell function. Frontiers in Bioscience, 1(12): 344-357, 2007.

• GORJAO R, VERLENGIA R, LIMA TM, SORIANO FG, BOAVENTURA MF, KANUNFRE CC, PERES CM, SAMPAIO SC, OTTON R, FOLADOR A, MARTINS EF, PITHON-CURI TC, PORTIOLLI EP, NEWSHOLME P, CURI R.Effect of docosahexaenoic acid-rich fish oil supplementation on human leukocyte function. Clinical Nutrition, 25 (6): 923-938, 2006.

• CURY-BOAVENTURA MF, GORJÃO R, DE LIMA TM, NEWSHOLME P, CURI R. Comparative Toxicity of oleic and linoleic acids on human lymphocytes. Life Sci.78(13):1448-56, 2006.

• CURI R, LAGRANHA CJ, DOI SQ, SELLITTI DF, PROCOPIO J, PITHON-CURI TC, CORLESS M, NEWSHOLME P. Molecular mechanisms of glutamine action. Journal of Cellular Physiology, 28 (1): 567 – 571, 2005.

• CURI R, LAGRANHA CJ, DOI SQ, SELLITTI DF, PROCOPIO J, PITHON-CURI TC, CORLESS M, NEWSHOLME P. Molecular mechanisms of glutamine action. J Cell Physiol. 204(2):392-401. Review, 2005.

• VERLENGIA R, GORJÃO R, KANUNFRE CC, BORDIN S, DE LIMA TM, MARTINS EF, NEWSHOLME P, CURI R. Effects of EPA and DHA on proliferation, cytokine production, and gene expression in Raji cells. Lipids. 39(9):857-64, 2004.

• PITHON-CURI TC, SCHUMAKER RI, FREITAS JJS, LAGRANHA C, NEWSHOLME P, PALANCH AC, DOI SQ, CURI R. Glutamine delays spontaneous apoptosis in neutrophils. American Journal Physiology, 284 (6): C1355-1361, 2003.

• NEWSHOLME P, PROCOPIO J, LIMA MM, PITHON-CURI TC, CURI R. Glutamine and glutamate-their central role in cell metabolism and function. Cell Biochemistry and Function, 21(1): 1-9, 2003.

• NEWSHOLME P, LIMA MM, PROCOPIO J, PITHON-CURI TC, DOI SQ, BAZOTTE RB, CURI R. Glutamine and glutamate as vital metabolites. Brazilian Journal of Medical and Biological Research, 36 (2): 153-163, 2003.

• GARCIA C, PITHON-CURI TC, FIRMANO ML, PIRES DE MELO M, NEWSHOLME P, CURI R. Effect of edrenaline on glucose and metabolism and superoxide production by rat neutrophils. Clinical Science, 96: 549-555, 1999.

• CURI R, NEWSHOLME P, PITHON-CURI TC, PIRES DE MELO M, GARCIA C, HOMEM DE BITENCOURT JR PI, GUIMARÃES ARP. Metabolic fate of glutamine in lymphocytes, macrophages and neutrophils Brazilian Journal of Medical and Biological Research, 32: 15-21, 1999.

• NEWSHOLME P, CURI R, PITHON-CURI TC, MURPHY CJ, GARCIA C, PIRES DE MELO M. Glutamine metabolism by lymphocytes, macrophages, and neutrophils: its importance in health and disease. Journal Nutrition Biochemistry, 10 (6): 316-24. 1999.

 

Uniformed Services University of the Health and Science, Bethesda, Washington – DC, EUA.

Department of Medicine, Division of Nephrology
Profa. Dra. Sonia Quatelli Doi

Division of Endocrinology
Prof. Dr. Donald Sellitti

Abaixo segue a lista dos artigos publicados, resultado da cooperação e intercâmbio há 11 anos entre a Profa. Dra. Tania Cristina Pithon-Curi e Profa Dra Adriana Cristina Levada-Pires com a Profa. Dra. Sonia Quatelli Doi e Prof. Dr. Donald Sellitti:

• LAMBERTUCCI AC; LAMBERTUCCI RH; HIRABARA SM; CURI R; MORISCOT AS; ALBA-LOUREIRO TC; GUIMARÃES-FERREIRA L; LEVADA-PIRES AC; VASCONCELOS DAA; SELLITTI DF; PITHON-CURI TC. Glutamine Supplementation Stimulates Protein-Synthetic and Inhibits Protein-Degradative Signaling Pathways in Skeletal Muscle of Diabetic Rats. Plos One, v. 7, p. e50390, 2012.

• LAGRANHA CJ, DOI SQ, PITHON-CURI TC, CURI R, SELLITTI DF. Glutamine enhances glucose-induced mesangial cell proliferation. Amino Acids. 34 (4):683-685, 2008.

• SELLITTI DF, PUGGINA EF, LAGRANHA CJ, DOI SQ, PITHON-CURI TC, KOHN LD, SUZUKI K. TGF-beta-like transcriptional effects of thyroglobulin (Tg) in mouse mesangial cells. Endocrine Journal, 54: 449-458, 2007.

• PITHON-CURI TC, SELLITTI DF, CURI R, MACHADO MM, HIRSZEL P, DOI SQ. Requirement of Glutamine for expression of alpha-actin and type IV collagen in mesangial cells. Cell Biochemistry and Function, 24(3): 217-221, 2006.

• LAGRANHA CJ, LIMA TM, SENNA SM, DOI SQ, CURI R, PITHON-CURI TC. Effect of glutamine supplementation on the function of neutrophils from exercised rats. Cell Biochemistry and Function, 23 (2): 101-107, 2005.

• CURI R, LAGRANHA CJ, DOI SQ, SELLITTI DF, PROCOPIO J, PITHON-CURI TC, CORLESS M, NEWSHOLME P. Molecular mechanisms of glutamine action. Journal of Cellular Physiology, 28 (1): 567 – 571, 2005.

• LAGRANHA CJ, SENNA SM, DE LIMA TM, SILVA E, DOI SQ, CURI R, PITHON-CURI TC. Beneficial effect of glutamine on exercise-induced apoptosis of rat neutrophils. Med Sci Sports Exerc. 36(2):210-7, 2004.

• CURI R, LAGRANHA CJ, DOI SQ, SELLITTI DF, PROCOPIO J, PITHON-CURI TC. Glutamine-dependent changes in gene expression and protein activity. Cell Biochemistry and Function 23(2): 77-84, 2005.

• LAGRANHA CJ, SENNA SM, LIMA TM, SILVA EPP, DOI SQ, CURI R, PITHON-CURI TC. Glutamine administration prevents exercise-induced apoptosis of rat neutrophils. Medicine Science and Sports Exercise, 36 (2): 210-7, 2004.

• PITHON-CURI TC, SCHUMAKER RI, FREITAS JJS, LAGRANHA C, NEWSHOLME P, PALANCH AC, DOI SQ, CURI R. Glutamine delays spontaneous apoptosis in neutrophils. American Journal Physiology, 284 (6): C1355-61, 2003.

• NEWSHOLME P, LIMA MM, PROCOPIO J, PITHON-CURI TC, DOI SQ, BAZOTTE RB, CURI R. Glutamine and glutamate as vital metabolites. Brazilian Journal of Medical and Biological Research, 36 (2): 153-63, 2003.

• PITHON-CURI TC, LEVADA AC, LOPES LR, DOI SQ, CURI R. Glutamine plays a role in superoxide production and the expression of p47phox, p22phox and gp91phox in rat neutrophils. Clin Sci (Lond). 103(4):403-8, 2002.

Université de Genève, Suiça
Faculté de Médicine
Mitochondria and Metabolism Lab
Prof. Dr. Pierre Maechler

Docentes do programa com colaborações: Sandro Massao Hirabara

• HIRABARA SM, CURI R, MAECHLER P. Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells. Journal of Cellular Physiology (Print), v.222, p. 187-194, 2010.

Maastricht University Medical Center (Maastricht, Holanda)
Department of Human Biology, NUTRIM
Pesquisadores: Prof. Dr. Patrick Schrauwen e Prof. Dr. Joris Hoeks
Docentes do programa com colaborações: Sandro Massao Hirabara

University of California, (Davis, EUA)
Department of Neurobiology, Physiology and Behavior
Pesquisador: Profa. Dra. Sue C. Bodine

Docente do programa com colaborações: Sandro Massao Hirabara

Technische Universitat Munchen
School of Life Sciences Weihenstephan
Prof. Dr. Hannelore Daniel

Docentes do programa com colaborações: Tânia Cristina Pithon-Curi, Sandro Massao Hirabara e Renata Gorjão

A colaboração com o laboratório da Profa Dra Hannelore Daniel tem sido muito importante para a realização de análises de lipidômica em mulheres idosas praticantes de exercícios físicos, maratonistas e em modelos experimentais envolvendo diferentes protocolos de exercício físico.